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Monofilament Polydioxanone Synthetic Absorbable
Polydioxanone (PDO) monofilament synthetic absorbable, sterile surgical suture is prepared from the polyester, poly(p-dioxanone).
Characteristics
Polydioxanone (PDO) exhibits
Polydioxanone monofilament synthetic absorbable suture is indicated for use in soft tissue approximation, including use in pediatric cardiovascular and ophthalmic procedures. Polydioxanone suture is not indicated in adult cardiovascular tissue, microsurgery, and neural tissue. This suture is particularly useful when the combination of an absorbable suture and extended wound support is desirable.
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Mono-Dox synthetic absorbable suture elicits a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual absorption of Mono-Dox sutures occurs by means of hydrolysis.
Tensile Strength
Subcutaneous tissue implantation studies in rats indicate Mono-Dox suture retains approximately 95% of initial tensile strength at 2 weeks, 80-85% at 4 weeks and 75% at 6 weeks post implantation.
Absorption
Absorption begins as a loss of tensile strength without appreciable loss of mass. Absorption of Mono-Dox sutures is minimal until about the 60th day after implant and is essentially complete within 6-8 months.
Sterilization
Ethylene oxide.
Packaging
Polydioxanone suture is a synthetic absorbable monofilament and is dyed (violet) or undyed (milk white). It is available in sizes 7-0 through 2 (metic sizes 0.5-5). The suture is supplied sterile in precut lengths attached to various needle types in one- to three-dozen boxes, or non-needled on ligating reels.
Polydioxanone (PDO) exhibits
- Extended holding strength.
- Excellent handling, exceptional suppleness, and good knot security.
- Non-wicking, which helps reduce bacterial migration along suture line.
- FDA-approved D&C Violet No. 2 color for better visibility during surgery.
Polydioxanone monofilament synthetic absorbable suture is indicated for use in soft tissue approximation, including use in pediatric cardiovascular and ophthalmic procedures. Polydioxanone suture is not indicated in adult cardiovascular tissue, microsurgery, and neural tissue. This suture is particularly useful when the combination of an absorbable suture and extended wound support is desirable.
Actions
Mono-Dox synthetic absorbable suture elicits a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual absorption of Mono-Dox sutures occurs by means of hydrolysis.
Tensile Strength
Subcutaneous tissue implantation studies in rats indicate Mono-Dox suture retains approximately 95% of initial tensile strength at 2 weeks, 80-85% at 4 weeks and 75% at 6 weeks post implantation.
Absorption
Absorption begins as a loss of tensile strength without appreciable loss of mass. Absorption of Mono-Dox sutures is minimal until about the 60th day after implant and is essentially complete within 6-8 months.
Sterilization
Ethylene oxide.
Packaging
Polydioxanone suture is a synthetic absorbable monofilament and is dyed (violet) or undyed (milk white). It is available in sizes 7-0 through 2 (metic sizes 0.5-5). The suture is supplied sterile in precut lengths attached to various needle types in one- to three-dozen boxes, or non-needled on ligating reels.